A New Cohesive High-Concentrated Hyaluronic Acid Gel Filler: Correlation between Rheologic Properties and Clinical Indications

Background: Differences among the Available Hyaluronic (HA) gels are relevant to clinical practice as HA physicochemical characteristics guide cosmetic indications. Besides, literature still needs more information about correlation between gel’s behavior through their rheologic parameters and Objectives: We aim evaluate rheological properties of three with high concentrations HA, e.p.t.q. S100®, S300®, S500® (Jetema®) extrapolate results after applied skin. Methods: To correlate possible indications, presentations these were evaluated. The storage modulus (G’), loss (G”), tan δ, complex modulus, viscosity, cohesiveness measured by rheology. Results: non-Newtonian fluid pseudoplastic behavior. All them presented elastic liquids (G’>G”). S500 gel showed highest G’ modulus. S100 δ cohesiveness. S300 intermediary viscosity similar S500. Discussion: Due low is indicated for facial structuring lifting. On opposite, signal refinement. intermediate values point it lift or Conclusions: According results, we can assume that each has a specific indication, combination S500, S300, enables global treatment.